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March 25, 2024

Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation

Nature Chemical Biology, published March 25, 2024 Continue Reading

December 13, 2023

Harrington Family Honored: The Faces of Life-Saving New Medicines

The Harrington Family has been recognized in Cleveland Magazine's 2023 Faces of Cleveland as "The Faces of Life-Saving New Medicines" Continue Reading

December 08, 2023

Wisconsin scientists studying gene-editing tech to cure blindness

Similar technology is gaining regulatory approval to treat sickle cell disease and drawing research attention to treat a wide range of health concerns Continue Reading

December 05, 2023

An Enzyme that Selectively S-nitrosylates Proteins to Regulate Insulin Signaling

New cause of diabetes discovered, offering potential target for new classes of drugs to treat the disease Continue Reading

September 29, 2023

Aleta aims for pivotal US trial with CAR T-cell engager

Aleta hopes to initiate the registrational trial investigating ALETA-001 in B-cell malignancies in 2024/25. Continue Reading

April 14, 2023

UH and CWRU researchers breathe new life into oxygen-starved tissues

Researchers have found a promising new method for delivering oxygen to tissues damaged by disease by coupling nitric oxide, which dilates blood vessels, with the oxygen carrying molecule hemoglobin to help people living with a number of diseases. Continue Reading

April 12, 2023

UMass Chan Scientists Deliver siRNA Therapy to Lung

Harrington Scholar Dr. Khvorova and research team have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease. Continue Reading

February 23, 2023

Discovery of Potential New Way to Prevent Vision Loss

UVA Health School of Medicine scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss. Continue Reading

February 14, 2023

Broad ALS Targets Show Signs of Success in Treating Genetic and Sporadic Forms

Studies published from researchers at the biotech startup AcuraStem and the University of Southern California validated two potential drug targets in animal models of both genetic and sporadic ALS, paving the way for broad treatments. Continue Reading

February 10, 2023

Potential Therapeutic Target for Blood Cancers Discovered

Investigators discovered that a specific complex drives cell proliferation in different forms of blood cancers called mutated myeloproliferative neoplasms (MPNs), suggesting the complex could serve as an ideal therapeutic target for blood cancer. Continue Reading

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