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November 16, 2021

WKYC TV Interview: Science Helps to Develop New Weapons in Fight Against COVID-19

As the COVID-19 pandemic continues on, scientists around the world are also developing new and creative ways to fight the virus. CLEVELAND — In 2020, during the height of the COVID-19 Pandemic, Harrington Discovery Institute at University Hospitals put out a call to scientists around the world: Send us your ideas to... Continue Reading

October 21, 2021

Researchers Home in on Biochemical Link Between Brain Injury, Alzheimer's Disease

Researchers have discovered an approach that could prevent nerve cells in the brain from deteriorating after a traumatic brain injury (TBI). A research team including scientists with the Geriatric Research Education and Clinical Center at the Louis Stokes Cleveland VA Medical Center identified the approach for preventing nerve... Continue Reading

October 18, 2021

Researchers Awarded $12 Million to Pursue Personalized Therapies for Severe Asthma

INDIANAPOLIS— A group of researchers led by Indiana University School of Medicine’s Benjamin Gaston, MD, has been awarded a research program project grant (P01) from the National Heart, Lung and Blood Institute. The award amounts to just over $12 million over the next five years and will fund the development of... Continue Reading

October 11, 2021

Tackling Dystonia with an Approved Drug

Dystonias are a group of chronic movement–disabling disorders for which highly effective oral medications or disease-modifying therapies are lacking. The availability of an oral drug with disease-modifying potential would transform the current treatment landscape. 2015 Harrington Scholar-Innovator Nicole Calakos, MD, PhD... Continue Reading

October 11, 2021

New Study Finds Therapeutic Treatment Option for Metabolic Syndrome, Obesity

Metabolic syndrome is a cluster of conditions and includes obesity and can be dangerous as it increases the risk for heart disease, stroke, diabetes and other diseases. A Harrington Discovery Institute research team proves successful use of “anti-obesity” drug in pre-clinical animal models. “The last piece of... Continue Reading

October 11, 2021

Small-Molecule Suppression of Calpastatin Degradation Reduces Neuropathology in Models of Huntington’s Disease

Huntington’s Disease (HD) is a fatal neurological disorder caused by a trinucleotide CAG repeat expansion in the N-terminal exon 1 of the huntingtin (Htt) gene. HD manifests as uncontrolled involuntary movements accompanied by progressive motor and cognitive deficits, psychiatric disturbance, and dementia. There is no... Continue Reading

August 18, 2021

New Study Finds Therapeutic Treatment Option for Metabolic Syndrome, Obesity

Harrington Discovery Institute at University Hospitals research team proves successful use of “anti-obesity” drug in pre-clinical animal models CLEVELAND—Metabolic syndrome is a cluster of conditions and includes obesity, and can be dangerous as it increases the risk for heart disease, stroke, diabetes and... Continue Reading

August 02, 2021

Nominations Open for 9th Annual Harrington Prize for Innovation in Medicine

Harrington Discovery Institute and the ASCI collaborate to recognize an outstanding achievement of a physician-scientist globally CLEVELAND, Ohio – National and international nominations are being sought for the 2022 Harrington Prize for Innovation in Medicine, which honors a physician-scientist who has moved science... Continue Reading

July 13, 2021

Harrington Discovery Institute Announces 2021 Scholar-Innovator Award Recipients

Eight physician-scientists from U.S. and Canada selected for novel treatments in numerous major disease areas CLEVELAND, Ohio – The Harrington Discovery Institute at University Hospitals in Cleveland, Ohio, today announced the 2021 class of Harrington Scholar-Innovators. The scholar awards will support a diverse set of... Continue Reading

July 01, 2021

The Alzheimer’s Drug Discovery Foundation and Harrington Discovery Institute to Support Promising Research to Restore Brain Function in People with Alzheimer’s Disease

Dr. Paul Fish of University College London and Dr. Paul Worley of Johns Hopkins University selected for their work aimed at restoring brain function NEW YORK, NY – The Alzheimer’s Drug Discovery Foundation (ADDF) and Harrington Discovery Institute at University Hospitals in Cleveland have granted ADDF-Harrington... Continue Reading