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January 20, 2019

A Major Grant to Keep Aging Brains Healthy

Andrew A. Pieper, MD, PhD, Director, Center for Brain Health Medicines at Harrington Discovery Institute is program director for the $9.6 million grant, entitled Restoring the Neurovascular Unit, awarded to three members of Harrington Discovery Institute at University Hospitals in 2018 for their research into brain health related to aging. This funding from the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment will help these researchers identify new ways to protect people from cognitive decline. The distinguished team is comprised of Jonathan S. Stamler, MD, President of Harrington Discovery Institute and Dr. Pieper.

The Harrington Discovery Institute team is working to better understand the interface between the cardiovascular system and the brain, known as the neurovascular unit. This interface is where the blood vascular system terminates
in the brain, and is composed of cells from both the brain and the vasculature. At this location, these cells interact in unique ways distinct from their separate functions elsewhere in the brain and vascular system.

*This post was updated on 12/01/2021

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