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August 18, 2022

Harrington Scholar Developing a Universal Therapeutic that can Prevent and Treat All Strains of Influenza A

Harrington Scholar Developing a Universal Therapeutic that can Prevent and Treat All Strains of Influenza A Continue Reading

August 09, 2022

A prescription for exercise: Scientists want to help you find the best workout for your brain

Jonathan Stamler, M.D., President of Harrington Discovery Institute, is developing an exercise wearable to help personalize exercise, to help minimize the risks of dementia. Continue Reading

January 24, 2022

Linda and Les Vinney Scholar Program to Support New Treatments for Alzheimer’s Disease

Linda and Les Vinney committed $1.25 million to establish the Linda and Les Vinney Scholar Program at Harrington Discovery Institute's Center for Brain Health Medicine, which will support new treatments for patients living with Alzheimer's disease. The gift also creates the Linda and Les Vinney Acceleration Awards, which will... Continue Reading

January 18, 2022

Harrington Discovery Institute Advances COVID-19 Treatments

Four Medicines in Clinical Trials and More in the Pipeline Continue Reading

November 16, 2021

WKYC TV Interview: Science Helps to Develop New Weapons in Fight Against COVID-19

CLEVELAND — In 2020, during the height of the COVID-19 Pandemic, Harrington Discovery Institute at University Hospitals put out a call to scientists around the world: Send us your ideas to battle the coronavirus and we may fund your research.They received three hundred applications.All they needed was a fraction of the money... Continue Reading

October 21, 2021

Researchers Home in on Biochemical Link Between Brain Injury, Alzheimer's Disease

Researchers have discovered an approach that could prevent nerve cells in the brain from deteriorating after a traumatic brain injury (TBI).A research team including scientists with the Geriatric Research Education and Clinical Center at the Louis Stokes Cleveland VA Medical Center identified the approach for preventing nerve... Continue Reading

October 11, 2021

Tackling Dystonia with an Approved Drug

Dystonias are a group of chronic movement–disabling disorders for which highly effective oral medications or disease-modifying therapies are lacking. The availability of an oral drug with disease-modifying potential would transform the current treatment landscape. 2015 Harrington Scholar-Innovator Nicole Calakos, MD, PhD... Continue Reading

October 11, 2021

New Study Finds Therapeutic Treatment Option for Metabolic Syndrome, Obesity

Metabolic syndrome is a cluster of conditions and includes obesity and can be dangerous as it increases the risk for heart disease, stroke, diabetes and other diseases. A Harrington Discovery Institute research team proves successful use of “anti-obesity” drug in pre-clinical animal models.“The last piece of the puzzle is... Continue Reading

October 11, 2021

Small-Molecule Suppression of Calpastatin Degradation Reduces Neuropathology in Models of Huntington’s Disease

Huntington’s Disease (HD) is a fatal neurological disorder caused by a trinucleotide CAG repeat expansion in the N-terminal exon 1 of the huntingtin (Htt) gene. HD manifests as uncontrolled involuntary movements accompanied by progressive motor and cognitive deficits, psychiatric disturbance, and dementia. There is no therapy... Continue Reading

August 19, 2021

Oxford-Harrington Partnership Targets FA as First Priority

Scientists on either side of the Atlantic have teamed up, through the new (OHC), to address unmet needs in rare disease research and deliver “major clinical impact” to patients.And now, the international collaboration between the University of Oxford, in England, and the Harrington Discovery Institute, in Cleveland, Ohio... Continue Reading