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May 17, 2024

The Oxford-Harrington Rare Disease Centre Announces Newly Funded Grant Award Programmes to Develop New Therapies for Friedreich’s Ataxia

The Oxford-Harrington Rare Disease Centre (‘OHC’), a partnership (between the University of Oxford, UK and Harrington Discovery Institute at University Hospitals, Cleveland, Ohio) aimed at driving cutting-edge rare disease breakthroughs, is pleased to announce that it has received a philanthropic donation of up to £650,000... Continue Reading

April 16, 2024

Harrington Discovery Institute Announces 2024 Scholar-Innovator Award Recipients

10 physician-scientists have been selected for drug development grant to advance discoveries into the clinic Continue Reading

March 25, 2024

Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation

Nature Chemical Biology, published March 25, 2024 Continue Reading

March 19, 2024

International Harrington Prize Awarded to Dr. Arlene Sharpe

2024 Harrington Prize for Innovation in Medicine Recognizes Pioneering Work in Immunology Continue Reading

February 08, 2024

The Alzheimer’s Drug Discovery Foundation and Harrington Discovery Institute to Support Promising New Drug Development Addressing the Biology of Aging Among People with Alzheimer’s Disease

Dr. Paul Tesar of Case Western Reserve University and Dr. Donald F. Weaver of University Health Network selected for their work targeting novel pathways in Alzheimer’s Continue Reading

February 06, 2024

Oxford-Harrington Rare Disease Centre Opens Call for Proposals

New Scholar Award Accelerates Novel Therapies for Rare Diseases Continue Reading

January 03, 2024

Jonathan Stamler, MD, Named Fellow of the 2023 National Academy of Inventors

Co-founder and president of Harrington Discovery Institute at University Hospitals receives highest professional distinction awarded solely to inventors Continue Reading

December 21, 2023

Allyx Therapeutics Lead Compound ALX-001 is Safe and Tolerable at Doses, Achieving Full Brain Target Engagement in Healthy Older Adults

The study showed that all doses of ALX-001 were well tolerated, up to and including levels high enough to achieve full brain target engagement, supporting the company’s plans to continue clinical development for the treatment of Alzheimer’s disease. Continue Reading

December 21, 2023

An Enzyme that Selectively S-Nitrosylates Proteins to Regulate Insulin Signaling

An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling.Zhou HL, Grimmett ZW, Venetos NM, Stomberski CT, Qian Z, McLaughlin PJ, Bansal PK, Zhang R, Reynolds JD, Premont RT, Stamler JS.Cell. 2023 Dec 21;186(26):5812-5825.e21. doi: 10.1016/j.cell.2023.11.009. PMID: 38056462 Continue Reading

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